Joseph Audie
Assistant Professor of Biochemistry
Phone: 203-371-7986
Email: audiej@sacredheart.edu

Education
B.S. Bioengineering, Hofstra University (1995)
M.S. Biomedical Engineering, University of Connecticut (2001)
Ph.D. Biophysics, SUNY Stony Brook (2006)
Areas of Specialization
Protein biophysics

Description of Research Interests
My scientific research interests and activities are primarily focused on (1) developing a theoretical understanding of protein-protein and protein-peptide recognition (2) developing computational methods to predict and explain protein-protein and protein-peptide interactions and (3) applying computational methods to identify and optimize peptide-based and peptide-derived drug leads.

Additionally, I am interested in exploring and understanding the relationship between modern empirical science and the philosophy of Aristotle and St. Thomas Aquinas.

Selected Publications
1. Audie, J., Continued development of an empirical function for predicting and rationalizing protein-protein binding affinities. Biophys Chem, 2009. 143(3): p. 139-44.
2. Audie, J., Development and validation of an empirical free energy function for calculating protein-protein binding free energy surfaces. Biophys Chem, 2009. 139(2-3): p. 84-91.
3. Audie, J. and S. Scarlata, A novel empirical free energy function that explains and predicts protein-protein binding affinities. Biophys Chem, 2007. 129(2-3): p. 198-211.

Primary Teaching Responsibilities
CH533 Biophysical Chemistry, CH597 Computational and Bioanalytical Chemistry, CH103 The Human Community and Scientific Discovery: the natural Sciences